Table 3 of Miyadera, Mol Vis 2009; 15:2287-2305.

Table 3. Genotype-phenotype correlation in MLHDs of sporadic retinopathy cases and controls.


Phenotype		 RPGRIP1 genotype Total number
of dogs
+/+ +/− −/−
Control 81 (41%) 87 (44%) 32 (16%) 200
PRA 6 (10%) 6 (10%) 47 (80%) 59
SARD 4 (80%) 0 (0%) 1 (20%) 5
Total 89(33%) 93 (35%) 82 (33%) 264

Correlation of the retinal phenotype and the RPGRIP1 insertion genotype were studied in dogs of the Japanese MLHD pet population. Sporadic cases of PRA and sudden acquired retinal degeneration (SARD), and controls with no apparent visual dysfunction showed substantial discordance seen in controls dog with RGPRIP1−/− and PRA cases that were not RPGRIP1−/−. RPGRIP1 genotypes are denoted as follows: wildtype homozygote (+/+); heterozygote (+/−); insertion homozygote (−/−).

Miyadera, Mol Vis 2009; 15:2287-2305. http://www.molvis.org/molvis/v15/a246

©2009 Molecular Vision http://www.molvis.org/molvis/

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