Figure 7. ERG responses and fundus photograph of Beagles with the RPGRIP1 insertion variant. Bilateral scotopic (top) and photopic (middle) ERG recordings and fundus photograph of the left eye (OS; bottom) of three Beagles: a 5y RPGRIP1^+/−L dog (A and D), a 2.8y RPGRIP^−L/−L (B and E), and another 2.8y RPGRIP1^−L/−L dog (C). Scotopic responses to a series of light stimuli are displayed with increasing light intensity from top to bottom differing by 1 log cd/m² up to 18,400 cd/m². The photopic response was recorded with 31 Hz flicker stimuli of 35,900 cd/m². Note the apparently normal fundus appearance in the RPGRIP1^−L/−L dog (E) with undetectable cone response (B). OD indicates right eye.