Figure 10. Marker analysis in PRA affected RPGRIP1^−/− MLHDs. Polymorphic markers in the cord1 critical region on CFA15 were analyzed in PRA affected RPGRIP1^−/− MLHDs. The 12 dogs shown are representative of the haplotypes of 47 sporadic cases and six cases from Family K studied. Alleles shared by the majority of the dogs are highlighted in blue (referred to as “common allele” in Figure 9 and Figure 11) and other highlighted colors mark less common alleles. Variants in CAMC15.029 and 034 could be the result of mutation events, rather than recombination since the markers flanking them are the “common alleles.” Therefore, the region of homozygosity was delimited by markers CAMC15.041 and CAMC15.031. The symbol (-) for the marker RPGRIP1 insertion represents the RPGRIP1 insertion allele. ND indicates that the genotype was not determined.