Figure 5. Effect of pioglitazone on collagen I and fibronectin expression. The expression of collagen I and fibronectin by corneal fibroblasts
was analyzed by western blotting after treatment with or without pioglitazone (1, 3, and, 10 μm). A: Representative immunoblot for collagen I and fibronectin. Lane 1, control; lane 2, 1 μm; lane 3, 3 μm; lane 4, 10 μm. B: Quantitative analysis of collagen I and fibronectin protein expression by densitometry from cells described in A. Values are the means±SD from three separate experiments. The asterisk indicates p<0.05 compared with control.