Table 4 of Micheal, Mol Vis 2009; 15:2268-2278. Table 4 of Micheal, Mol Vis 2009; 15:2268-2278.
Table 4. Combine genoype analysis of methyltetrahydrofolate reductase C677T polymorphism with primary closed angle glaucoma and controls.
| Combined Subjects | ||||||
|---|---|---|---|---|---|---|
| C677T | A1298C | Controls (143) | PCAG (122) | OR (95%CI) | p (χ2) | p (χ2) |
| CC | AA | 14 (10%) | 22 (18%) | 0.49 (0.24-1.00) | 0.05 (5.8) | 0.005 (20.1) |
| CC | AC | 66 (46%) | 52 (43%) | 1.15 (0.71-1.87) | ||
| CC | CC | 21 (15%) | 10 (8%) | 1.93 (0.88-4.20) | ||
| CT | AA | 6 (4%) | 7 (6%) | 1.72 (0.25-2.10) | 0.43 (1.7) | |
| CT | AC | 30 (21%) | 17 (14%) | 1.64 (0.86-3.12) | ||
| CT | CC | 5 (3%) | 2 (2%) | 2.17 (0.48-9.87) | ||
| TT | AA | 0 (0%) | 5 (4%) | 0.00 (0.00-0.63) | 0.03 (6.9) | |
| TT | AC | 1 (1%) | 7 (6%) | 0.12 (0.02-0.74) | ||
| TT | CC | 0* (0%) | 0 (0%) | -------- | ||
| Subjects of Pathan Ethnicity | ||||||
| C677T | A1298C | Controls (70) | PCAG (61) | OR (95%CI) | p (χ2) | p (χ2) |
| CC | AA | 11 (16%) | 5 (8%) | 2.09 (0.71-6.12) | 0.62 (0.97) | 0.19 (9.8) |
| CC | AC | 33 (47%) | 25 (41%) | 1.28 (0.64-2.56) | ||
| CC | CC | 9 (13%) | 8 (13%) | 0.98 (0.36-2.64) | ||
| CT | AA | 6 (9%) | 2 (3%) | 2.77 (0.61-12.41) | 0.09 (4.8) | |
| CT | AC | 10 (14%) | 15 (25%) | 0.51 (0.21-1.23) | ||
| CT | CC | 0 | 2 (3%) | 0.00 (0.00-1.67) | ||
| TT | AA | 0 | 1 (2%) | 0.00 (0.00-3.58) | N/A | |
| TT | AC | 1 (1%) | 3 (5%) | 0.28 (0.04-2.03) | ||
| TT | CC | 0 | 0 | --------- | ||
| Subjects of Punjabi Ethnicity | ||||||
| C677T | A1298C | Controls (73) | PCAG (61) | OR (95%CI) | p (χ2) | p (χ2) |
| CC | AA | 3 (4%) | 17 (28%) | 0.11 (0.03-0.38) | 0.001 (17.5) | <0.001 (49.6) |
| CC | AC | 33 (45%) | 27 (44%) | 1.04 (0.53-2.05) | ||
| CC | CC | 12 (17%) | 2 (3%) | 5.80 (1.38-24.03) | ||
| CT | AA | 0 | 5 (8%) | 0.00 (0.00-0.61) | <0.001(21.4) | |
| CT | AC | 20 (27%) | 2 (3%) | 11.13 (2.74-44.64) | ||
| CT | CC | 5 (7%) | 0 | ---------- | ||
| TT | AA | 0 | 4 (7%) | 0.00(0.00-0.77) | N/A | |
| TT | AC | 0 | 4 (7%) | 0.00(0.00-0.77) | ||
| TT | CC | 0 | 0 | ---------- | ||