Table 2 of Micheal, Mol Vis 2009; 15:2268-2278. Table 2 of Micheal, Mol Vis 2009; 15:2268-2278.
Table 2. Comparison of genotype frequencies of methyltetrahydrofolate reductase A1298C polymorphism with primary open angle glaucoma, primary closed angle glaucoma and controls.
| Collective Subjects | |||||||
|---|---|---|---|---|---|---|---|
Genotype |
Controls (143) |
POAG (173) |
OR (95%CI) |
p (χ2) |
PCAG (122) |
OR (95%CI) |
p (χ2) |
| AA | 20 (14%) | 35 (20%) | 0.64 (0.35-1.16) | 0.25 (2.7) | 34 (28%) | 0.42 (0.23-0.78) | 0.007 (9.7) |
| AC | 97 (68%) | 114 (66%) | 1.09 (0.68-1.74) | 76 (62%) | 1.28 (0.77-2.12) | ||
| CC | 26 (18%) | 24 (14%) | 1.38 (0.76-2.51) | 12 (10%) | 2.04 (0.99-4.18) | ||
| Subjects of Pathan Ethnicity | |||||||
Genotype |
Control (70) |
POAG (96) |
OR (95%CI) |
p (χ2) |
PCAG (61) |
OR (95%CI) |
p (χ2) |
| AA | 17 (24%) | 29 (30%) | 0.74 (0.37-1.48) | 0.19 (3.3) | 8 (13%) | 2.12 (0.86-5.23) | 0.26 (2.7) |
| AC | 44 (63%) | 62 (65%) | 0.93 (0.49-1.75) | 43 (71%) | 0.71 (0.34-1.47) | ||
| CC | 9 (13%) | 5 (5%) | 2.68 (0.89-8.01) | 10 (16%) | 0.75 (0.29-1.95) | ||
| Subjects of Punjabi Ethnicity | |||||||
Genotype |
Control (73) |
POAG (77) |
OR (95%CI) |
p (χ2) |
PCAG (61) |
OR (95%CI) |
p (χ2) |
| AA | 3 (4%) | 6 (8%) | 0.51 (0.13-1.94) | 0.60 (1.01) | 26 (43%) | 0.06 (0.02-0.19) | <0.001(33.9) |
| AC | 53 (73%) | 52 (68%) | 1.28 (0.63-2.55) | 33 (54%) | 2.25 (1.10-4.59) | ||
| CC | 17 (23%) | 19 (25%) | 0.93 (0.44-1.95) | 2 (3%) | 8.95 (2.18-36.21) | ||