Mice with streptozotocin-induced diabetes (STZID) had lower weights when compared to controls after 5 weeks, but the difference was not statistically significant. The differences in weight between control and insulin treatment (p=0.0004) and control and Nω-nitro-L-arginine methyl ester (L-NAME; p=0.03) were significant. Blood glucose levels were significantly elevated in diabetes (p<0.0001) and this was significantly lowered by insulin, although it was still significantly higher than control (p<0.0001). L-NAME or aminoguanidine (AG) did not appear to affect blood glucose levels and were not significantly different from untreated diabetic. Values are presented±SEM.