Table 1 of Lam, Mol Vis 2009; 15:2217-2229.


Table 1. Animal table: optic nerve transection and ocular hypertension.

Optic Nerve Transection






Duration




      Immunoreactivity
in treated
eye band
      of   Treated   Hemisphere       GFAP Mac-1
  ID#   Species treatment
  eye   processed       LGN V1 LGN V1
ONT 1 (AP75) Rhesus 14 days R R       NS ++ NS NS
ONT 2 (32676) Rhesus 14 days R L       + ++ + ++
ONT 3 (AR 96) Rhesus 28 days R L       ++ ++ NS NS
ONT 4 (19069) Rhesus 28 days R L       ++ NS NS NS
ONT 5 (AP39) Rhesus 28 days L R       NS + NS ++
ONT 6 (Rh168) Rhesus 28 days R L       ++ ++ + +
Ocular Hypertension (>30 mmHg)








Tx eye mean


Tx eye






Immunoreactivity
in treated
eye band
      IOP mmHg
cup/disk
    Treated   Hemisphere GFAP Mac-1
ID#
  Species   Duration   (C eye) (C eye)
Integral
  eye processed
LGN V1 LGN V1
GL 1 (534) Cynomolgus 14 days 48 (16) 0.4 (0.4) 672 R L NS + NS NS
GL 2 (452) Cynomolgus 40 days 51 (16) na (0.3) 2040 R L NS ++ NS NS
GL 3 (AI 34) Rhesus 55 days 46 (18) 0.9 (0.2) 2530 R R ++ ++ - -
GL 4 (529) Cynomolgus 56 days 47 (14) 0.9 (0.2) 2632 R R ++ ++ - -
GL 5 (570) Cynomolgus 45 days 40 (17) 0.9 (0.3) 1800 R R NS ++ NS NS
GL 6 (AS02) Rhesus 58 days 35 (18) 0.5 (0.3) 2030 L L ++ ++ - -