Figure 3. Photomicrographs of coronal sections of LGN from OHT brains. A: Section stained for CO histochemistry demonstrates reduced CO activity in ipsilateral eye layers (Layers 2, 3, 5). B: Serial section stained for GFAP immunohistochemistry demonstrates denser reaction product in the contralateral eye layers (Layers 1, 4, 6). C: Section stained for MAC-1 immunohistochemistry demonstrating uniform labeling throughout all LGN layers. Arrows point to high power photographs (100X) are shown and contrast staining in treated and normal eye bands for CO (D, E), GFAP (F, G), or MAC-1 (H, I) immunoreactivity. Note astrocytic profiles and processes in F and lack of labeled profiles in H and I.