Table 3 of Radhakrishnan, Mol Vis 2009; 15:2146-2154.

Table 3. Represents the list of oncomirs in uveal melanoma, targeting tumor suppressor genes.




Tumor suppressor gene identified in other tumors and disorders
▀miR-586 6p12.3 CDKNIC 11p15.5 Cylin dependent kinase inhibitor 1c,Rhabdoid tumor [23]
▀miR-493* 14q32.1 PDGFRL 8p22-p21.3 PDGF receptor beta-like tumor suppressor, Melanoma [24]
▀miR-377 14q32.1 CAV1 7q31.1 Caveolin 1, caveolae protein, Lung carcinoma [25]
▀miR-376c 14q32.1 CDKN1A 6p21.2 Cyclin dependent kinase inhibitor 1A, Laryngeal squamous cell carcinoma [26]
▀miR-369-3p 14q32.1 FZD6 8q22.3-q23.1 Frizzled homolog 6, melanocyte physiology, Uveal melanoma [13]
▀miR-34c-5p 11q23.1 TGFBR2 3p22 Tumor growth factor beta receptor 2, Colon cancer [27]
▀miR-26a-2* 12q14.1 EXLT3 8p21 Exotoses( multiple) like-3, Bone tumor [28]
▀mir-218 4p15.31 HYAL1 3p21.31 Hyaluronoglucosaminidase 1, Head and neck squamous cell carcinoma [29]
▀mir-19b-1* 13q31.3 RB 1 13q14.2 Retinoblastoma 1 [30]
▀mir-181a* 1q31.3 BRCA2 13q12.3 Breast cancer type2 susceptibility protein, Breast cancer [31]
▀mir-154 14q32.31 NEK1 4q33 (Never in mitosis gene a)-related kinase 1 [32]
▀miR-133a 18q11.2 DLEC1 3p22-p21.3 Deleted in lung and esophagael cancer, Gastrointestinal cancer [33]
▀miR-129* 7q32.1 TSSC1 2p25.3 Tumor suppressing subtransferable candidate 1 [34]
▀mir-10a 17q21.32 LATS1 6q25.1 Larger tumor suppressor, homolog1 [35]
▀mir-1 1q13.33 PINX1 8p23.1 PIN2–interacting protein 1 [36]
▀Let-7e 19q13.33 GAS1 9q21.3-q22 Growth arrest specific 1, Melanoma [37]
●mir-885-5p 3p25.3 PDGFRL 8p22-p21.3 Platelet–derived growth factor beta like tumor suppressor [24]
●miR-585 5q35.1 RPS29 14q22.1 Ribosomal protein S29, colorectal cancer [38]
●mir-640 19p13.41 S100A2 2q14.3 S100 calcium binding protein A2, Head and neck cancer [39]
●miR-512-5p 19q13.41 BIN-1 2q14.3 Bridging integrator, prostate cancer [40]
●mir-556-5p 1q23.3 TP53 17p13.1 Tumor suppressor protein P53, Osteoscarcoma [41]
●mir-135b* 1q32.1 HYAL1 3p21.3-p21.2 Hyaluronoglucosaminidase 1, Head and neck squamous cell carcinoma [29]
●mir-325 Xq21.1 PTPRG 3p14.2 Protein tyrosine phosphatase receptor type G, Nasopharyngeal carcinoma [42]
●mir-99a* 21q21.1 SEMA3B 3p21.31 Sema domain(Ig)short basic domain secreted, Lung cancer [43]
●miR33a 22q13.2 TSC2 16p13.3 Tuberous sclerosis protein 2, Lymphangioleiomyomatosis [44]