Table 2 of Radhakrishnan, Mol Vis 2009; 15:2146-2154. Table 2 of Radhakrishnan, Mol Vis 2009; 15:2146-2154.
Table 2. The list of oncomirs in uveal melanoma targeting metastasis suppressor genes.
miRNA |
Chromosome allocation |
Metastatic suppressor genes |
Chromosomal location |
Metastatic suppressor gene identified in other tumors |
|---|---|---|---|---|
| ■miR-495 | 14q32.31 | DLC1 | 8p22 | Deleted in liver cancer 1, Hepatocellular carcinoma [19] |
| ■miR-18a | 13q31.3 | BRMS1 | 11q13-q13.2 | Breast cancer metastasis suppressor 1; Non-small cell lung cancer [20] |
| ● miR-196a* | 12q13.3 | CASP8 | 2q33.34 | Caspase 8, apoptosis-related cysteine peptidase; Neuroblastoma [21] |
| ● miR-549 | 15q25.1 | LZTS1 | 8p22 | Leucine zipper putative tumor suppressor 1, Uveal melanoma [14] |
| ● miR-497* | 17p13.3 | KISS1 | 1q32.1 | KiSS-1 metastasis suppressor; Gastric cancer [22] |