Figure 4. Effect of CNTF on gene expression profile of RPCs by qPCR. With CNTF treatment, expression of the proliferation marker K_i-67 decreased sharply while other progenitor markers were downregulated slightly or remained unchanged, with the exception of vimentin and Hes5, which increased (A). Most lineage and differentiation markers (B, C) were upregulated and tended to progressively increase from day 1 to day 7. Abbreviations: day 1 (d1), day 3 (d3), day 5 (d5), day 7 (d7). The error bars show standard deviation.