Figure 5 of Produit-Zengaffinen, Mol Vis 2009; 15:2101-2110.

Figure 5. Bcl-2 family members are similarly regulated at the mRNA and protein levels. Ischemia modified Bax, Bak, Bcl-2, and Bcl-xL mRNA (A) and protein expression (B) 24 h after reperfusion relative to 3 h. A: Proapototic Bax and Bak mRNAs expression was increased, whereas antiapoptotic Bcl-xL was decreased and Bcl-2 expression unaltered 24 h after I/R. B: At the protein level, Bax expression was significantly increased but there was no modification in Bak, Bcl-2, or Bcl-xL when measured 24 h after I/R. Green columns mark ischemic/ctrl ratio (i/c) ratio at 3 h, and light blue columns indicate i/c ratio at 24 h. Error bars represent SEM, where *p<0.05, ***p<0.001 in control versus ischemic retinas as measured by Student's t-test.