Figure 1. Ischemia reduced Bax, Bak, and Bcl-x_L mRNAs expression 3 h after I/R. Bax (A), Bak (B), Bcl-2 (C), and Bcl-x_L (D) mRNAs expression was measured by qPCR 3 h after reperfusion. At 3 h after reperfusion, ischemia decreased Bax (A), Bak (B), and Bcl-x_L (D) expression but did not alter the Bcl-2 mRNA level (C). E and F showed no modification in Bax:Bcl-2 nor Bax:Bcl-x_L mRNA ratios in the early phase after I/R. Brown columns denote control retinas (n=6), and beige columns denote ischemic retinas (n=10). Error bars represent SEM, where *p<0.05, ***p<0.001 in control versus ischemic retinas as measured by Student's t-test.