Figure 2. Slit-lamp photographs. A:
Right eye of patient II-7 from Family 1. Note the significant, heavy,
corneal vascularization sparing the nasal area. The iris base is very
thin, almost invisible, a typical feature of aniridia. The patient was
aphakic since cataract surgery performed in childhood. Best-corrected
visual acuity was 0.1. B: Right eye patient III-4 from Family 1
showing heavy corneal vascularization (pannus) and superior dislocation
of the lens. Almost no iris residual tissue is visible, as typically
seen in aniridia. Note as well the small anterior polar cataract and
the associated faint peripheral cortical opacities. C and D:
Right and left eye of patient IV-3 from Family 2. Note the bilateral
posterior polar cataract shaped like the petals of a flower and the
superior lens dislocation. E and F: Fundus photographs.
Right and left eye of patient IV-1 from Family 2. Foveal hypoplasia is
observed with macular pigment epithelium alterations.