Figure 1. Localization of expression of exon trapped X chromosome clone 1 (ETX1) in human trabecular meshwork. A: Merged image of exon trapped X chromosome clone 1 (ETX1) with secondary Cy5 antibody (magenta) and 4',6-diamidino-2-phenylindole (DAPI) in the normal trabecular meshwork (TM). B: The normal TM image stained only for ETX1 (secondary coupled with Cy5; magenta) C: The merged image (ETX1 in magenta) in glaucomatous TM as indicated. Glaucomatous TM shows increased expression of ETX1 as compared to normal TM as in A. D:Glaucomatous TM labeled by ETX1 antibody coupled to Cy5, with arrows indicating areas of hyperfluorescence compared to normal tissue. SC, Schlemm’s canal.