Figure 4 of Singh, Mol Vis 2009; 15:2050-2060.


Figure 4. Cu2+-induced self-aggregation of αA-crystallin, G98R αA-crystallin, and their mixed oligomer. Aggregation of 0.1 mg/ml of αA-crystallin (○), G98R αA-crystallin (●), and their mixed oligomer (◓) as a function of increasing Cu2+ concentration at 37 °C in buffer B was monitored by light scattering at 465 nm expressed in arbitrary units (AU). G98R αA-crystallin and its mixed oligomer with wild type protein exhibit increased vulnerability to Cu2+-induced self-aggregation.