Figure 1. Allele Frequencies for rs1042522 in POAG patients and controls by sex and age. A: The frequency of the arginine allele (G) and proline allele (C) in men and women. In both men and women, the frequency of the arginine allele (G) is higher in POAG patients than controls. B: Subjects were divided into two age groups: group 1 from 50-64 years old and group 2 from 65-99 years old. In both age groups, the frequency of the arginine allele (G) is higher in POAG patients than controls.