Figure 7 of Lagziel, Mol Vis 2009; 15:1843-1857.


Figure 7. Immunolocalization of CDH23 in photoreceptor cells of monkey retina. A: CDH23 immunoreactivity was detected with antisera TF7 in the IS and in the synaptic terminals of the OPL of photoreceptor cells. Some staining is evident in the photoreceptor cell bodies of the ONL and INL. B: No immunoreactivity was observed in the controls stained only with secondary antibody. C: In a higher magnification, CDH23 staining is visible in the evenly spaced IS of cone-shaped photoreceptors (asterisks) and in the regions between the IS and OS where the ciliary apparatus is present (arrows). Rod photoreceptors are also positively stained (seen as thin long strings). The dark brown pigment in the upper portion of A and B is melanin of the RPE. C: Scale bars represent 5 µM. Magnification: A, B 400× and C 1000×. Abbreviations: retinal pigment epithelium (RPE), outer segment (OS), inner segment (IS), outer nuclear layer (ONL), outer plexiform layer (OPL), inner nuclear layer (INL).