Table 4 of Park, Mol Vis 2009; 15:200-207.


Table 4. Comparison of the association observed between AMD and the SERPING1 variant rs2511989 in four subject groups

Subject group
(genotyping platform)
Mayo subjects
(TaqMan)
AREDS subjects
(TaqMan)
Ennis et al. (UK)
subjects (Illumina)
Ennis et al. (US)
subjects (TaqMan)
Subjects Case Control Case Control Case Control Case Control
No. of participants 470 310 1221 295 479 479 248 252









Allele count (%)







G 569 (61) 363 (59) 1435 (59) 357 (61) 597 (63) 500 (52) 322 (65) 282 (56)
A 371 (39) 257 (41) 1007 (41) 233 (39) 355 (37) 454 (48) 174 (35) 222 (44)









Genotype count (%)







GG 179 (38) 103 (33) 436 (36) 115 (39) 191 (40) 132 (28) 100 (40) 79 (31)
GA 211 (45) 157 (51) 563 (46) 127 (43) 215 (45) 236 (50) 122 (49) 124 (49)
AA 80 (17) 50 (16) 222 (18) 53 (18) 70 (15) 109 (23) 26 (11) 49 (19)









P-values







Allele 0.46 0.41 5.4E-06 0.0037
Genotype 0.44 0.45 4.0E-05 0.0080