Table 2 of Lin, Mol Vis 2009; 15:1774-1780.

Table 2. Association between genotype distributions of CHRM1 polymorphisms and individuals with high myopia.



Polymorphisms		 Individuals
with myopia
> 6.0D (%)		 Individuals
with myopia
< 0.5D (%)

OR

95% CI*		 p value#/
Cp-value##
rs11823728 (S1)
G/G 187 (96.3) 106 (97.2) 1 - 0.74/2.96
A/G 6 (3.1) 3 (2.8) 1.13 0.28–4.63
A/A 1 (0.5) 0 (0) -

rs544978 (S2)
G/G 145 (74.7) 76 (69.7) 1 - 5.99×10−7/2.40× 10−6
A/G 46 (23.7) 14 (12.8) 1.72 0.89–3.33
A/A 3 (1.5) 19 (17.4) 0.08 0.02–0.29
rs2186410 (S3)
A/A 150 (77.3) 89 (81.7) 1 - 0.03/0.12
A/G 24 (12.3) 4 (3.7) 3.56 1.2–10.59
G/G 20 (10.3) 16 (14.7) 0.74 0.37–1.51
rs542269 (S4)
A/A 149 (76.8) 91 (83.5) 1 - 5.96×10−9/2.38×10−8
A/G 43 (22.2) 3 (2.8) 8.75 2.64–29.04
G/G 2 (1.0) 15 (13.8) 0.08 0.02–0.36

Genotype frequencies were compared between individuals with myopia greater than 6.00 D and less than 0.5 D. The asterisk indicates CI=confidence interval. #The χ2 test or Fisher's exact test was performed to obtain the p value. It was considered statistically significant if p was less than 0.05. ##Cp-value, p-value corrected by Bonferroni correction.

Lin, Mol Vis 2009; 15:1774-1780. http://www.molvis.org/molvis/v15/a187

©2009 Molecular Vision http://www.molvis.org/molvis/

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