Figure 4. Conjunctival impression cytology stained by cresyl violet and impression cytology scale. ^BAC+Latanoprost (A) induced numerous polymorphonuclear inflammatory cells as islets (red circles). ^BAC+Travoprost (B) showed epithelial damage with inflammatory islets. ^BAC+Bimatoprost (C) induced slight epithelial cell disorganization. PBS (D) and LCEm (E) rabbit eyes presented almost normal epithelial patterns without any obvious inflammatory cell infiltration (original size 40X). IC scale (F) showed that the highest toxicity was found in ^BAC+latanoprost-, ^BAC+travoprost-, and ^BAC+bimatoprost-treated eyes. LCEm- and PBS-instilled groups were similar. The asterisk indicates a p<0.0005 compared with ^BAC+latanoprost. The sharp indicates a p<0.01 compared with ^BAC+travoprost and the filled diamond indicates a p<0.05 compared with ^BAC+bimatoprost.