Molecular Vision: Rosen, Mol Vis 2009; 15:1673-1679. Table 2

Table 2. Urinary 6-sulphatoxymelatonin/creatinine level in age-related macular degeneration patients and controls.

Statistical adjustment	Odds ratio	95% CI	p-value
Not adjusted for any factor	0.72	0.58–0.90	0.004
Adjusted for age only	0.73	0.58–0.91	0.006
Adjusted for smoking history only	0.7	0.53–0.89	0.005
Adjusted for histories of cancer and coronary heart disease only	0.7	0.55–0.89	0.003
Adjusted for all the above factors	0.65	0.48–0.88	0.005

The odds-ratios and 95% confidence intervals (CI) of urinary aMT6s levels between AMD and the controls were estimated by an unconditional logistic regression model. To control potential confounding factors, the odds-ratio and CI were adjusted by age, and histories of smoking, cancer and coronary artery disease using multiple logistic regression model. The difference of aMT6s level between AMD patients and the controls was still present after adjusting for all these factors, indicating that urinary aMT6s level in AMD patients is significantly lower than that of the controls.