Figure 7. Effects of HP on the expression of PDE7B mRNA in human ONH astrocytes. PDE7B expression is significantly (p<0.05, asterisk) increased in AA astrocytes (black bars) compared to control after treatment with HP for 3 or 6 h. On the other hand, HP treatment significantly (p<0.05 asterisk) decreases expression of PDE7B in CA astrocytes (white bars) compared to control after treatment with HP for 3 or 6 h. In these experiments n=8 for controls and n=3 for the HP-treated groups. Error bars indicate SEM.