Figure 6. Effect of HP on CAP2 and PTHLH mRNAs in human ONH astrocytes. A: CAP2 expression is not affected by HP (3–6 h) in either AA (blue bars) or CA (white bars) astrocytes. B: PTHLH expression is higher in AA astrocytes (black bars) compared to CA astrocytes (white bars) after treatment with HP for 6 h (p<0.05, asterisk). Expression was determined using quantitative RT–PCR. Expression within each group was not significantly affected by 3–6 h of HP treatment. In these experiments n=8 for controls and n=3 for the HP-treated groups. Error bars indicate SEM.