Table 4 of Lin, Mol Vis 2009; 15:1655-1663. Table 4 of Lin, Mol Vis 2009; 15:1655-1663.
Table 4. The genotype distribution of polymorphisms between the high myopia group and control subjects.
| SNP | Genotype | Controls | Cases | OR (95% CI) | p-value/ Cp-value# | Allele | Controls | Cases | OR (95% CI) | p-value/ Cp-value# |
|---|---|---|---|---|---|---|---|---|---|---|
| TGF-β2rs7550232 | n | 94 | 195 | n | 188 | 390 | ||||
| (S1) | A/A | 63 (67%) | 160 (82%) | 1.00 | 0.015/0.03 | A | 156 (83%) | 353 (91%) | 1.00 | 0.0089/0.0178 |
| C/C | 1 (1%) | 2 (1%) | 0.79 (0.07–8.84) | C | 32 (17%) | 37 (9%) | 0.51(0.31–0.85) | |||
| A/C | 30 (32%) | 33 (17%) | 0.43 (0.24–0.77) | |||||||
| HWEc2 | 1.583 | 0.042 | ||||||||
| TGF-β2rs991967 | n | 94 | 195 | 0.2189/0.4378 | n | 188 | 390 | |||
| (S2) | C/C | 61 (65%) | 109 (56%) | 1.00 | C | 152 (81%) | 290 (74%) | 1.00 | 0.0847/0.1694 | |
| A/A | 3 (3%) | 14 (7%) | 2.48 (0.68–9.04) | A | 36 (19%) | 100 (26%) | 1.41(0.91–2.17) | |||
| A/C | 30 (32%) | 72 (37%) | 1.30 (0.76–2.21) | |||||||
| HWEc2 | 0.089 | 0.19 | ||||||||
| bFGFrs308395 | n | 94 | 195 | 0.1078/0.2156 | n | 188 | 390 | |||
| (S3) | C/C | 70 (74%) | 152 (78%) | 1.00 | C | 164 (87%) | 341 (87%) | 1.00 | 1.0/1.0 | |
| G/G | 0 | 6 (3%) | - | G | 24 (13%) | 49 (13%) | 0.97 (0.58–1.62) | |||
| C/G | 24 (26%) | 37 (19%) | 0.69 (0.38–1.24) | |||||||
| HWEc2 | 2.01 | 3.63 | ||||||||
| bFGFrs41348645 | n | 94 | 195 | 0.0647/0.1294 | n | 188 | 390 | |||
| (S4) | G/G | 2 (2%) | 8 (4%) | 1.00 | G | 48 (26%) | 131 (34%) | 1.00 | 0.0479/0.0958 | |
| A/A | 48 (51%) | 72 (37%) | 2.91 (0.59–14.32) | A | 140 (74%) | 259 (66%) | 1.52 (1.03–2.25) | |||
| A/G | 44 (47%) | 115 (59%) | 1.71 (1.03–2.85) | |||||||
| HWEc2 | 5.01* | 20.2* | ||||||||
| FMODrs7543148 | n | 94 | 195 | n | 188 | 390 | ||||
| (S5) | G/G | 11 (11.7%) | 12 (6.1%) | 1 | 0.181/0.362 | G | 63 (34%) | 106 (27.2%) | 1 | 0.129 |
| A/A | 42 (44.6%) | 101 (51.8%) | 0.44 (0.19–1.08) | A | 125 (66%) | 284 (72.8%) | 0.72(0.45–1.05) | |||
| A/G | 41 (43.6%) | 82(42.1%) | 0.58 (0.22–1.37) | |||||||
| HWEc2 | 0.042 | 0.76 |