Table 3 of Wang, Mol Vis 2009; 15:181-186. Table 3 of Wang, Mol Vis 2009; 15:181-186.
Table 3. Sequence variations in MFRP observed in 51 patients with hyperopia.
Variations |
Location |
Change |
Effect |
Hyperopia (n=51) |
Normal control (n=96) |
|---|---|---|---|---|---|
| c.1–31G>A | 5′ | GGA-GAA | rs883247 | 26 | ND |
| c.55–14_55–13ins GTAT | Intron 1 | insertGTAT | No effect | 3 | 7* |
| c.192C>G | Exon 3 | CGC-CGG | Arg-Arg | 1 | 0 |
| c.406G>A | Exon 4 | GTG-ATG | rs3814762 | 20 | ND |
| c.492C>T | Exon 5 | TAC-TAT | rs36015759 | 20 | 36* |
| c.496C>G | Exon 5 | CCC-GCC | Pro-Ala | 1 | 3* |
| c.540T>C | Exon 5 | CAT-CAC | rs2510143 | 51 | 95* |
| c.664C>A | Exon 6 | CCC-ACC | Pro-Thr | 1 | 0 |
| c.669G>A | Exon 6 | ACG-ACA | Thr-Thr | 2 | 0 |
| c.770G>A | Exon 6 | CGC-CAC | Arg-His | 1 | 2* |
| c.954G>A | Exon 8 | CTG-CTA | rs35885438 | 1 | ND |