Figure 3. Photography of corneal histological features of the proband. A: A hematoxylin and eosin stained section shows epithelial atrophy, epithelial hyperplasia, and the considerable extent of the subepithelial and superficial stromal deposits of eosinophilic material. Original magnification 100X. B: Nodular subepithelial amorphous deposits stain positive with periodic acid-Schiff. Original magnification 100X. C: Congo red-positive accumulations were within or beneath the epithelium and within the anterior stroma. In some areas, Congo red-positive deposits accumulated to form gelatinous drop-like masses. Original magnification 100X. D: Higher magnification revealed band-like structures with a spike-like pattern just beneath the epithelium. Original magnification 400X. E: Congo red staining under polarized light revealed typical apple-green birefringence in epithelial and subepithelial regions, indicative of amyloid. Original magnification 100X.