Table 5 of Sullivan, Mol Vis 2009; 15:1553-1572. Table 5 of Sullivan, Mol Vis 2009; 15:1553-1572.
Table 5. Influence of testosterone on the expression of gene ontologies in the female meibomian gland.
Ontology |
Testosterone genes ↑ |
Placebo genes ↑ |
Testosterone z-score |
Placebo z-score |
|---|---|---|---|---|
| Biological Process | ||||
| cellular catabolic process | 66 | 12 | 5.53 | -0.5 |
| oxidation reduction | 53 | 5 | 5.46 | -1.72 |
| protein transport | 45 | 3 | 3.44 | -2.49 |
| cell communication | 72 | 48 | -4.85 | 0.47 |
| signal transduction | 58 | 41 | -5.16 | 0.16 |
| regulation of biological process | 151 | 96 | -6.67 | 1.34 |
| immune response | 16 | 24 | -1.26 | 5.6 |
| organ development | 40 | 50 | -4.34 | 4.43 |
| response to stimulus | 56 | 51 | -3.32 | 3.68 |
| protein transport | 45 | 3 | 3.44 | -2.49 |
| protein localization | 49 | 4 | 3.15 | -2.53 |
| macromolecule localization | 51 | 4 | 3.25 | -2.62 |
| Molecular Function | ||||
| oxidoreductase activity | 57 | 8 | 5.81 | -0.88 |
| catalytic activity | 258 | 58 | 5.36 | -2.7 |
| peptidase activity | 33 | 10 | 2.4 | 0.51 |
| DNA binding | 39 | 35 | -4.57 | 1.33 |
| molecular transducer activity | 31 | 32 | -4.63 | 1.56 |
| signal transducer activity | 31 | 32 | -4.63 | 1.56 |
| receptor binding | 18 | 19 | -2.05 | 2.59 |
| receptor activity | 23 | 29 | -4.5 | 2.05 |
| nucleotide binding | 80 | 19 | 0.06 | -2.28 |
| Cellular Component | ||||
| mitochondrion | 82 | 11 | 6.19 | -1.2 |
| cytoplasm | 341 | 76 | 6.1 | -2.67 |
| organelle membrane | 59 | 10 | 5.64 | -0.18 |
| cytoskeleton | 21 | 15 | -2.76 | 0.62 |
| nucleus | 149 | 65 | -3.02 | 0.15 |
| plasma membrane | 53 | 51 | -6.25 | 2.21 |
| extracellular space | 8 | 16 | -2.57 | 3.83 |
| plasma membrane part | 20 | 33 | -5.21 | 3.22 |
| extracellular region part | 29 | 19 | -0.44 | 2.49 |
| intracellular part | 425 | 124 | 2.81 | -2.17 |
| cytoplasmic part | 235 | 40 | 7.44 | -2.47 |
| cytoplasm | 341 | 76 | 6.1 | -2.67 |