Table 4 of Sullivan, Mol Vis 2009; 15:1553-1572.


Table 4. Impact of testosterone on the expression of gene ontologies in the female lacrimal gland.


Ontology
Testosterone
genes ↑
Placebo
genes ↑
Testosterone
z-score
Placebo
z-score
Biological process
cell cycle 54 48 4.42 -1.43
mitotic cell cycle 25 18 4.02 -0.94
DNA metabolic process 35 25 3.78 -2.01
protein metabolic process 98 248 -2.06 2.45
anatomical structure development 81 173 -2.51 -1.66
multicellular organismal process 119 231 -2.52 -2.88

translation 5 62 -2.64 7.28
cellular protein metabolic process 96 242 -2.02 2.36
proteolysis 30 89 -1.59 2.06
protein amino acid phosphorylation 30 36 -0.44 -3.47
signal transduction 113 152 0.67 -4.06
cell communication 122 169 0.14 -4.59
Molecular function
transferase activity, transferring acyl groups 15 5 3.18 -2.35
small GTPase regulator activity 13 8 2.47 -1.38
vitamin binding 10 12 2.07 0.73
endopeptidase activity 8 38 -2.04 1.88
calcium ion binding 24 71 -2.2 0.59

structural constituent of ribosome 5 51 -0.8 11.45
structural molecule activity 12 75 -1.62 7.63
hydrogen ion transmembrane transporter activity 5 18 0.73 4.68
ribonucleotide binding 65 95 -0.53 -3.21
signal transducer activity 64 91 -0.37 -3.24
transferase activity 83 97 1.63 -3.28
Cellular component
chromosome 28 11 3.91 -3.17
nucleolus 13 18 2.84 2.1
nucleus 207 329 2.43 -0.23
plasma membrane part 40 77 -2.25 -2.76

ribosome 6 59 -1.15 10.91
ribonucleoprotein complex 13 85 -1.69 8.59
macromolecular complex 80 228 -1.12 5.79
chromosomal part 22 9 3.39 -2.77
intrinsic to membrane 163 281 -0.89 -2.58
membrane 230 417 -1.46 -2.43