Table 3 of Sullivan, Mol Vis 2009; 15:1553-1572.


Table 3. Testosterone influence on gene expression ratios in the female meibomian gland.

Accession number Gene Ratio p value Ontology
Testosterone>Placebo
NM_030265 Kv channel interacting protein 4 8.8 0.0134 transport
NM_011351 sema domain, transmembrane domain, and cytoplasmic domain, (semaphorin) 6C 4.0 0.0036 multicellular organismal development
NM_008161 glutathione peroxidase 3 3.0 0.0063 response to oxidative stress
NM_008362 interleukin 1 receptor, type I 2.4 0.0021 signal transduction
NM_026523 neuromedin B 2.3 0.0019 neuropeptide signaling pathway
NM_008288 hydroxysteroid 11β dehydrogenase 1 2.2 0.0123 lipid metabolic process
NM_008324 indoleamine-pyrrole 2,3 dioxygenase 2.2 0.0380 positive regulation of T cell tolerance induction
AA832579 a disintegrin-like and metallopeptidase with thrombospondin type 1 motif, 2 2.2 0.0003 proteolysis
NM_010174 fatty acid binding protein 3 2.2 0.0409 phosphatidylcholine biosynthetic process
U08020 collagen, type I, α1 2.2 0.0004 negative regulation of cell-substrate adhesion
Placebo>Testosterone
NM_007894 eosinophil-associated, ribonuclease A family, member 1 4.3 0.0016 nucleic acid binding
NM_011468 small proline-rich protein 2A 3.3 0.0082 regulation of cell shape
NM_013650 S100 calcium binding protein A8 2.8 0.0332 chemotaxis
NM_022984 resistin 2.4 0.0136 hormone activity
NM_009154 sema domain, seven thrombospondin repeats, trans-membrane domain and short cytoplasmic domain 2.1 0.0077 multicellular organismal development
AK005197 kin of IRRE like 3 2.0 0.0003 hemopoiesis
NM_010449 homeo box A1 1.9 0.0441 transcription
NM_008620 guanylate binding protein 4 1.9 0.0231 biological_process
NM_031184 GLIS family zinc finger 2 1.9 0.0206 transcription
AK011647 protein kinase, cAMP dependent regulatory, type IIβ 1.9 0.0021 regulation of protein amino acid phosphorylation