Molecular Vision: Sullivan, Mol Vis 2009; 15:1553-1572. Table 2

Table 2. Testosterone effect on gene expression ratios in the female lacrimal gland.

Accession number	Gene	Ratio	p value	Ontology
Testosterone>Placebo
NM_019515	neuromedin	975.7	0.0003	cell communication
AF071068	dopa decarboxylase	86.2	0.0005	amino acid metabolism
NM_008957	patched homolog 1	64.5	0.0000	regulation of growth
NM_009021	retinoic acid induced 1	40.6	0.0033	transcription
NM_010643	kallikrein 1-related peptidase b24	38.8	0.0001	proteolysis
NM_053178	acyl-CoA synthetase bubblegum family member 1	37.6	0.0023	very-long-chain fatty acid metabolic process
NM_007936	Eph receptor A4	29.4	0.0001	neurogenesis
NM_007413	adenosine A2b receptor	28.2	0.0001	signal transduction
NM_007556	bone morphogenetic protein 6	27.2	0.0082	transmembrane receptor protein serine/threonine kinase signaling pathway
AK007577	chordin-like 2	27.2	0.0005	transmembrane receptor protein serine/threonine kinase signaling pathway
Placebo>Testosterone
NM_018874	pancreatic lipase related protein 1	81.1	0.0001	metabolism
NM_018781	early growth response 3	19.8	0.0401	transcription
NM_009714	asialoglycoprotein receptor 1	15.7	0.0118	vesicle-mediated transport
NM_023186	chitinase, acidic	15.1	0.0480	polysaccharide catabolic process
NM_008456	kallikrein 1-related peptidase b5	15.1	0.0288	proteolysis
NM_007446	amylase 1, salivary	12.5	0.0418	carbohydrate metabolic process
NM_011105	polycystin	14.8	0.0015	cell communication
AK002477	plasma membrane proteolipid	12.0	0.0004	transport
NM_022305	UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1	9.2	0.0003	metabolism
NM_007409	alcohol dehydrogenase 1 (class I)	9.1	0.0049	metabolism

The accession number is the sequence identity of the gene fragment expressed on the CodeLink Bioarray. This sequence appears in the nucleotide database of the National Center for Biotechnology Information (NCBI). Relative ratios were calculated by comparing the degree of gene expression in lacrimal glands from placebo- and testosterone-treated ovariectomized mice. Genes listed had a signal intensity average of >5.0 in at least one group, a comparative p value (between glands) of <0.05 and a known identity. These ratios were generated from non- and log-transformed data.