Figure 3. Hydrophobicity change of R15S CRYGD. The prediction by ProtScale analysis at Expasy indicated an increase of local hydrophobicity around the site of R15S mutation (Circle in panel B). A: The curve showed the hydrophobicity score of each amino acid of wildtype CRYGD. B: The curve was the hydrophobicity of R15S CRYGD. At the position of the 15th amino acid and its neighboring locations, the hydrophobicity scores increased which was indicated by the circle.