Figure 4. In vitro and ex vivo filamentation of C. albicans∆sap4-6 mutant strain. Compared with SC5314 and VE175, this mutant strain exhibited low but intermediate capabilities to produce filaments around fungal colonies. At day 1 postinoculation, the mutant strain formed hyphae in the superficial stroma at pH 7.3 but did not produce filamentous forms at pH 8.0.