Figure 1. The COOH-terminal sequences of αB-crystallin and its mutants. A: The amino acid sequences from Q151 to the COOH-terminal of wild-type (WT) αB-crystallin and its truncated mutants. Various truncated mutants of porcine αB-crystallin have been constructed in order to study the functions of the COOH-terminal extension fragment of αB-crystallin. The amino acid (E164) of these mutants is underlined and marked with an asterisk. B: The amino acid sequences from I160 to the COOH-terminus of wild-type αB-crystallin and its mutants. Various mutants were constructed to study effects of amino-acid substitutions at position 174 and 175. The amino acid (P173) of these mutants is underlined and marked with an asterisk.