Figure 5. JWH015, but not ACEA, attenuates
H2O2-induced cytotoxicity. A: Inhibition
of H2O2-induced decrease in ARPE-19 cell
viability by JWH015. ARPE-19 cells were pretreated with 0–10 μM JWH015
for 15 min before exposure to 200 μM H2O2 for 24
h, and their viability was measured by the MTT assay. Asterisk (*)
represents the correlation significant at the p<0.05 level and
suggest a significant increase in cell viability as compared to H2O2-treated
group. B: ACEA showed no significant effect on H2O2-induced
decrease in cell viability. ARPE-19 cells were pretreated with 0–10 μM
ACEA for 15 min before exposure to 200 μM H2O2
for 24 h, and their viability was measured by MTT assay.