Figure 8. Effects of SP600125 on HOG-LDL-induced apoptosis. Administration of 10 µM SP600125, an inhibitor of Jun N-terminal kinase (JNK) signaling pathways, did not block apoptosis in human retinal capillary pericytes (HRCP) induced by highly oxidized-glycated low density lipoprotein (HOG-LDL). Bars represent mean±SD of three separate experiments. The asterisk represents p<0.05 compared to serum-free medium (SFM).