Figure 7. LDL increases JNK phosphorylation. A: This panel shows representative western immunoblots from one experiment, and densitometric data from three experiments (mean±SD) describing the time course of LDL-induced phosphorylation of the two isoforms of JNK, p54, and p46 (P-JNK and T-JNK means phosphorylated and total JNK). B: This panel shows representative western immunoblots from one experiment, and densitometric data from three experiments (mean±SD) describing dose effects of LDL on p54 and p46 JNK phosphorylation. N-LDL and HOG-LDL had similar effects on phosphorylation of both JNK isoforms. Control immunosignal (T-JNK) bands (both isoforms) were detected in the same gels as P-JNK after stripping and re-probing. In both panels, densitometric calculations of P-JNK were corrected for T-JNK. Asterisk represents p<0.05 compared to control (Time 0 or Dose 0).