Figure 4. Effects of U0126 on
HOG-LDL-induced apoptosis. Administration of 10 µM U0126, an inhibitor
of extracellular signal-regulated kinase (ERK) signaling pathways, did
not decrease apoptosis induced by at 200 mg/l highly oxidized-glycated
low density lipoprotein (HOG-LDL). Bars represent mean±SD of three
separate experiments. The asterisk indicates p<0.05 compared to
serum-free medium (SFM).