Figure 3. LDL increases ERK
phosphorylation. A: This panel shows representative western
immunoblots from one experiment, and densitometric data from three
experiments (mean±SD) describing the time course of LDL-induced ERK
phosphorylation (P-ERK and T-ERK means phosphorylated and total ERK). B:
This panel shows representative western immunoblots from one
experiment, and densitometric data from three experiments (mean±SD)
describing dose effects of LDL on ERK phosphorylation. N-LDL and
HOG-LDL had similar effects on ERK1/2 phosphorylation. Control
immunosignal (T-ERK) bands were detected in the same gels as P-ERK
after stripping and re-probing. In both panels, densitometric
calculations of P-ERK were corrected for T-ERK. Asterisk represents
p<0.05 compared to control (Time 0 or Dose 0).