Figure 3. Partial least squares discriminant analysis (PLS-DA) of vitreous fluid NMR spectra from lens-induced uveitis and chronic uveitis
patients. A PLS-DA model was constructed to predict diagnostic groups.
A: Latent variable plot of the PLS-DA model, showing improved discrimination between LIU and chronic uveitis compared with
the PCA analysis (
Figure 2).
B: Prediction of the group membership from the PLSDA. The model was cross validated, and was able to predict the classes, LIU
and chronic uveitis, with sensitivity of 78% and specificity of 85%.