Table 2 of Mozaffarieh, Mol Vis 2009; 15:1194-1199.

Table 2. Descriptive statistics for the amount of DNA damage before and after PDT and ranibizumab treatment



Type of treatment		 Photodynamic therapy (PDT) Ranibizumab
Prior to
treatment
30 min
45 min
60 min
24 h		 Prior to
treatment
30 min
45 min
60 min
24 h
Mean 0.22 0.53 0.33 0.23 0.20 0.30 0.22 0.14 0.13 0.15
Median 0.19 0.46 0.28 0.21 0.19 0.24 0.19 0.14 0.16 0.16
StdDev 0.11 0.24 0.23 0.12 0.11 0.18 0.16 0.08 0.06 0.08
Minimum 0.14 0.36 0.10 0.13 0.13 0.12 0.08 0.06 0.06 0.06
Maximum 0.44 1.00 0.74 0.46 0.45 0.64 0.42 0.21 0.20 0.21
N 6 6 6 6 6 6 6 6 6 6
p value
p=0.004* ns ns ns ns ns ns ns ns

PDT induced a transient increase in the amount of single stranded DNA damage in the circulating leukocytes from 0.22 AU (before treatment) to 0.53 AU (30 min after treatment).The asterisk indicates a significant result was only obtained after 30 min.

Mozaffarieh, Mol Vis 2009; 15:1194-1199. http://www.molvis.org/molvis/v15/a127

©2009 Molecular Vision http://www.molvis.org/molvis/

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