Table 4 of Abhary, Mol Vis 2009; 15:1179-1184.

Table 4. Frequency of common haplotypes and association with blinding DR under additive and dominant genetic models.

T1DM

Haplotype
1
2
3
4
5
6
7
8
9
10		 Haplotype
frequency		 No DR
frequency		 Blinding DR
frequency		 Additive
p value		 Dominant
p value
1 T G T C C A C G C C 0.165 0.175 0.151 0.404 0.333
2 G A T T C G C A T C 0.205 0.218 0.184 0.429 0.616
3 T A C T A A T A C C 0.428 0.410 0.459 0.203 0.228
T2DM

Haplotype
1
2
3
4
5
6
7
8
9
10		 Haplotype
frequency		 No DR
frequency		 Blinding DR
frequency		 Additive
p value		 Dominant
p value
1 G A T T A A T A C T 0.041 0.045 0.034 0.822 0.818
2 T A C T A A T A C T 0.050 0.046 0.051 0.504 0.502
3 T G T C C A C G C C 0.151 0.143 0.162 0.556 0.466
4 G A T T C G C A T C 0.224 0.220 0.229 0.516 0.540
5 T A C T A A T A C C 0.397 0.392 0.410 0.863 0.941

SNPs are numbered as in Table 2 and the p-value for all haplotypes with a frequency >2% are given. Results have been adjusted for sex, diabetes type, duration of disease and HbA1c.

Abhary, Mol Vis 2009; 15:1179-1184. http://www.molvis.org/molvis/v15/a125

©2009 Molecular Vision http://www.molvis.org/molvis/

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