Figure 5. Effect of P2Y₂-R siRNA on Ap₄A-mediated corneal wound healing. A: A representative sequence of the progress in the corneal wound in the three different treatments (0.9% saline, 100 μM Ap₄A, and siRNA+100 μM Ap₄A) is shown. B: The graphs show the variation of the wounded area versus time and the estimated migration rates (EMR) in the three treatments. An asterisk means p<0.05 when compared to the control, and a double asterisk indicates p<0.01 when compared to the control.