Figure 5. Cellular distribution of Ogg1 protein in the retinal cells. Using an antibody raised against human 8-oxoguanine DNA glycosylase, immunostaining is detected in photoreceptor inner segments (A), outer nuclear layer (ONL, B), inner nuclear layer (INL, C) and ganglion cell layer (GCL, D). Ogg1 immunoreactivity was detected both in the cytoplasmic and nuclear compartments of the immunolabeled cells of GCL and INL. The staining seemed only cytoplasmic in photoreceptor cells, which also displayed a strong labeling in the inner segments (IS). Scale bar equals 20 μm in A, and 8 µm in B, C, and D. Abbreviations:, inner plexiform layer (IPL); outer segment (OS); outer plexiform layer (OPL); retinal pigment epithelium (RPE).