Molecular Vision: Lee, Mol Vis 2009; 15:1120-1126. Table 4

Table 4. Frequencies of the two-locus haplotype among three different populations.

rs1048661	rs3825942	Haplotype frequency
		Chinese		Japanese [28]		Caucasian [21]
		XFS/XFG (n=62)	Controls (n=171)	XFS/XFG (n=209)	Controls (n=172)	XFS/XFG (n=86)	Controls (n=2087)
T	G	0.476	0.556	0.947	0.506	0.22	0.34
G	G	0.516	0.363	0.039	0.365	0.74	0.51
G	A	0.008	0.082	0.014	0.129	0.05	0.15
Haplotype diversity (±SE)		0.511 (± 0.01)	0.554 (± 0.014)	0.102 (±0.02)	0.596 (± 0.014)	0.404 (±0.037)	0.602 (±0.004)

The two-locus haplotype frequencies in the Chinese, Japanese, and Caucasian are shown. Only one example is shown for Caucasians from a Caucasian Australian population for comparison with the two Asiatic populations. The distribution of the T-G, G-G, and G-A haplotypes were significantly different between cases and controls in both the Japanese and Caucasian studies shown here [21],[28]. In our present Chinese study, only the G-G and G-A haplotypes were significantly different between cases and controls. Haplotype diversity is also given for each sample. Haplotype diversity is a measure of the uniqueness of a particular haplotype in a given population. The haplotype diversity and its variance were calculated using the formula given within the indicated reference [39].