Table 2 of Lee, Mol Vis 2009; 15:1120-1126.

Table 2. Distribution of LOXL1 polymorphisms in pseudoexfoliation and control subjects.




SNP


Allele		 Allele count (frequency)
Allele
association
(p value)

OR
[95% CI]


Genotype		 Genotype count (frequency)
Genotype
association
(p value)
p value
OR
[95% CI]
XFS/XFG Cases
(n=62)		 Controls
(n=171)		 XFS/XFG cases
(n=62)		 Controls
(n=171)
rs1048661 *G 65 (0.524) 152 (0.444) 0.142 1.38
[0.91- 2.08]		 G-G 20 (0.323) 29 (0.169) 0.03 0.0173**
2.33 [1.2–4.54]
T 59 (0.476) 190 (0.556) T-G 25 (0.403) 94 (0.550)



T-T 17 (0.274) 48 (0.281)
rs3825942 A 1 (0.008) 28 (0.082) 0.0018 10.97
[1.48- 81.49]		 G-G 61 (0.984) 143 (0.84) 0.0013 0.0013
11.94 [1.59–89.78]
*G 123 (0.992) 314 (0.918) G-A 1 (0.016) 28 (0.16)
A-A 0 (0.00) 0 (0.00)

Allelic and genotype association testing results of rs1048661 and rs3825942 in LOXL1 for Chinese cases with combined pseudoexfoliation syndrome and controls are shown. The single asterisk indicates the risk allele of each SNP. The double asterisk indicates the p values and OR values for G-G versus T-G+T-T of rs1048661. Abbreviations: SNP=single nucleotide polymorphism; XFS=pseudoexfoliation syndrome; XFG=pseudoexfoliation glaucoma; n=number of subjects; OR=odds ratio; CI=confidence interval.

Lee, Mol Vis 2009; 15:1120-1126. http://www.molvis.org/molvis/v15/a119

©2009 Molecular Vision http://www.molvis.org/molvis/

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