Table 3 of Mabuchi, Mol Vis 2009; 15:1045-1049. Table 3 of Mabuchi, Mol Vis 2009; 15:1045-1049.
Table 3. Genotype and allele frequencies of rs1042522 and rs59758982 of tumor protein p53 (p53) in patients with POAG and control subjects.
p53 polymorphisms (rs number) |
Control (n=189) |
POAG | ||||
|---|---|---|---|---|---|---|
| NTG | HTG | |||||
| (n=213) | p value | (n=212) | p value | |||
| rs1042522 (Arg72Pro) |
Genotype | |||||
| CC | 23 (12.2) | 26 (12.2) | 25 (11.8) | |||
| CG | 83 (43.9) | 95 (44.6) | 0.99* | 102 (48.1) | 0.69* | |
| GG | 83 (43.9) | 92 (43.2) | 85 (40.1) | |||
| Allele | ||||||
| C | 129 (34.1) | 147 (34.5) | 152 (35.8) | |||
| G | 249 (65.9) | 279 (65.5) | 0.94** | 272 (64.2) | 0.66** | |
| rs59758982 (16 bp intron 3 insertion) |
Genotype | |||||
| Insertion/Insertion | 0 (0) | 0 (0) | 0 (0) | |||
| Insertion/Deletion | 0 (0) | 0 (0) | NA | 0 (0) | NA | |
| Deletion/Deletion | 189 (100) | 213 (100) | 212 (100) | |||
| Allele | ||||||
| Insertion | 0 (0) | 0 (0) | 0 (0) | |||
| Deletion | 378 (100) | 426 (100) | > 0.99** | 424 (100) | > 0.99** | |