Figure 1. Effects of exogenous Sonic hedgehog on the expression of angiogenic cytokine expression in cultures of mouse fibroblasts and Araki-Sasaki corneal epithelial cells. In both cell types, adding exogenous Shh does not affect mRNA expression levels of transforming growth factor β1 (TGFβ1; A), monocyte/macrophage-chemoattractant protein-1 (MCP-1; B), or vascular endothelial growth factor (VEGF; C).