Molecular Vision: Yanovitch, Mol Vis 2009; 15:1028-1035. Table 5

Table 5. Association analysis between haplotypes phenotypes.

Markers	High myopia		Mild-moderate myopia		Any myopia		Extreme myopia
Markers	SPH	SE	SPH	SE	SPH	SE	SPH	SE
rs12536657 rs2286194	0.6369	0.5721	0.0042 (0.021)	0.0055 (0.0275)	0.0094 (0.047)	0.0152	0.4933	0.3288
rs2286194 rs3735520	0.2958	0.2810	0.0342	0.1044	0.0358	0.0437	0.0871	0.0733
rs3735520 rs17501108	0.0800	0.0766	0.0289	0.0410	0.0062 (0.031)	0.0075 (0.0375)	0.1447	0.0481
rs12536657 rs2286194 rs3735520	0.2871	0.2844	0.0751	0.1107	0.0384	0.0345	0.3075	0.1607
rs2286194 rs3735520 rs17501108	0.1634	0.1577	0.0074 (0.037)	0.0627	0.0092 (0.046)	0.0057 (0.0285)	0.1661	0.0571

Association analysis between haplotypes and the following phenotypes using either sphere (SPH) or spherical equivalent (SE): 1) high myopia (≤-5.00 diopters [D]) 2) mild to moderate myopia (-0.50 to -5.00 D), 3) any myopia (≤-0.50 D) and 4) very high myopia (≤10.00 D) versus emmetropia. Significant global haplotypes were obtained by analyzing the possible allele combinations of either two or three loci. Locus nucleotide identity and p-value are identified for each combination with a significant p-value. Corrected p-values are in parentheses.